Johnson & Johnson
Johnson & Johnson
Johnson & Johnson ir globāls veselības aprūpes uzņēmums, kas darbojas farmācijas, medicīnas ierīču un patērētāju veselības jomā. Tā pētniecības un produktu izstrādes darbība ietver onkoloģijas, imunoloģijas, neirozinātnes, kā arī sirds un plaušu slimību zāles un terapijas, līdztekus MedTech risinājumiem sirds un asinsvadu aprūpei, ortopēdijai, ķirurģijai un redzes aprūpei. Uzņēmuma plašākā darbība ietver arī veselības un labklājības izglītību, liela mēroga ražošanu, darbu ar investoriem un globālas sociālās ietekmes iniciatīvas, radot iespējas zinātnes, klīniskā darba, inženierijas, ražošanas, komercdarbības un uzņēmuma funkcijās.

Senior/Executive Director, Oncology Reverse Translation

Lead reverse-translation research at Johnson & Johnson, converting clinical observations into actionable hypotheses for cancer drug development. Build teams, platforms, and strategies that strengthen the oncology pipeline.

Apraksts

  • Direct independent studies addressing high-priority mechanistic questions across oncology.
  • Set priorities across disease-focused and mechanism-focused research, including shelved programs.
  • Translate research findings into next-generation hypotheses and combination strategies with Discovery.
  • Address active mechanistic questions from translational research leads across solid and hematologic cancers.
  • Lead laboratory investigations into program efficacy, failure, and resistance.
  • Design and evaluate combination approaches to increase benefit and overcome resistance.
  • Establish and operate the laboratory while bringing disease-area program scientists together under unified leadership.
  • Oversee omics, functional and perturbation biology, in vitro and in vivo studies, and organoid platforms.
  • Contribute to translational research leadership and organization-wide scientific strategy.
  • Connect reverse translation with Discovery as the scientific liaison.
  • Collaborate with Medical Affairs and Commercial on portfolio and lifecycle priorities.
  • Advance mechanism-focused translational publications, including the Mechanism Series.
  • Mentor scientists and foster rigorous, open scientific debate.
  • Evaluate team performance by its influence on program and portfolio decisions.

Prasības

  • Doctorate in cancer biology, molecular biology, immunology, pharmacology, or a related discipline, such as a PhD, MD, or MD/PhD.
  • At least 10 years of oncology discovery or translational research experience for Senior Director roles, or 12 years for Executive Director roles, including hands-on laboratory leadership.
  • Broad expertise in mechanisms and modes of resistance, with demonstrated success converting clinical observations into testable laboratory hypotheses.
  • Experience building and managing wet-lab teams and operating omics and functional-characterization platforms.
  • Ability to work effectively between Discovery and Translational Research in a matrix spanning multiple disease areas.
  • Strong publication record as a first or senior author, together with clear scientific communication skills.
  • Preferred: expertise in multiomics, perturbation biology, organoid models, and computational data integration.
  • Preferred: experience extracting portfolio-relevant insights from shelved programs.
  • Preferred: demonstrated ability to design combination and resistance-reversal strategies across modalities.
  • Preferred: experience collaborating with Medical Affairs and Commercial on lifecycle-focused science.

Priekšrocības

  • Pension retirement plan.
  • 401(k) savings plan.
  • Long-term incentive program.
  • 120 vacation hours per calendar year.
  • 40 sick-time hours per calendar year, increasing to 48 hours in Colorado and 56 hours in Washington.
  • 13 paid holidays, including floating holidays, per calendar year.
  • Up to 40 hours of work, personal, and family time per calendar year.
  • 480 hours of parental leave within one year of a child’s birth, adoption, or foster placement.
  • Bereavement leave of 240 hours for an immediate family member or 40 hours for an extended family member per calendar year.
  • 80 caregiver-leave hours during a rolling 52-week period.
  • 32 volunteer-leave hours per calendar year.
  • 80 military spouse time-off hours per calendar year.
  • Inclusive interviews and disability accommodations.

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