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Senior/Executive Director, Oncology Reverse Translation
Lead reverse-translation research at Johnson & Johnson, converting clinical observations into actionable hypotheses for cancer drug development. Build teams, platforms, and strategies that strengthen the oncology pipeline.
विवरण
- Direct independent studies addressing high-priority mechanistic questions across oncology.
- Set priorities across disease-focused and mechanism-focused research, including shelved programs.
- Translate research findings into next-generation hypotheses and combination strategies with Discovery.
- Address active mechanistic questions from translational research leads across solid and hematologic cancers.
- Lead laboratory investigations into program efficacy, failure, and resistance.
- Design and evaluate combination approaches to increase benefit and overcome resistance.
- Establish and operate the laboratory while bringing disease-area program scientists together under unified leadership.
- Oversee omics, functional and perturbation biology, in vitro and in vivo studies, and organoid platforms.
- Contribute to translational research leadership and organization-wide scientific strategy.
- Connect reverse translation with Discovery as the scientific liaison.
- Collaborate with Medical Affairs and Commercial on portfolio and lifecycle priorities.
- Advance mechanism-focused translational publications, including the Mechanism Series.
- Mentor scientists and foster rigorous, open scientific debate.
- Evaluate team performance by its influence on program and portfolio decisions.
आवश्यकताएँ
- Doctorate in cancer biology, molecular biology, immunology, pharmacology, or a related discipline, such as a PhD, MD, or MD/PhD.
- At least 10 years of oncology discovery or translational research experience for Senior Director roles, or 12 years for Executive Director roles, including hands-on laboratory leadership.
- Broad expertise in mechanisms and modes of resistance, with demonstrated success converting clinical observations into testable laboratory hypotheses.
- Experience building and managing wet-lab teams and operating omics and functional-characterization platforms.
- Ability to work effectively between Discovery and Translational Research in a matrix spanning multiple disease areas.
- Strong publication record as a first or senior author, together with clear scientific communication skills.
- Preferred: expertise in multiomics, perturbation biology, organoid models, and computational data integration.
- Preferred: experience extracting portfolio-relevant insights from shelved programs.
- Preferred: demonstrated ability to design combination and resistance-reversal strategies across modalities.
- Preferred: experience collaborating with Medical Affairs and Commercial on lifecycle-focused science.
लाभ
- Pension retirement plan.
- 401(k) savings plan.
- Long-term incentive program.
- 120 vacation hours per calendar year.
- 40 sick-time hours per calendar year, increasing to 48 hours in Colorado and 56 hours in Washington.
- 13 paid holidays, including floating holidays, per calendar year.
- Up to 40 hours of work, personal, and family time per calendar year.
- 480 hours of parental leave within one year of a child’s birth, adoption, or foster placement.
- Bereavement leave of 240 hours for an immediate family member or 40 hours for an extended family member per calendar year.
- 80 caregiver-leave hours during a rolling 52-week period.
- 32 volunteer-leave hours per calendar year.
- 80 military spouse time-off hours per calendar year.
- Inclusive interviews and disability accommodations.
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