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Senior Director, Oncology Reverse Translation
Lead oncology reverse-translation research at Johnson & Johnson, connecting clinical observations with disease biology, therapeutic resistance, discovery, and pipeline strategy. Direct laboratory programs and scientific teams across solid and hematologic cancers.
विवरण
- Lead independent studies addressing high-priority mechanistic questions across oncology
- Set priorities across disease-focused, cross-MOA, MOA-focused, cross-disease, and shelved-program research
- Translate findings into next-generation hypotheses and combination strategies that support Discovery pipeline growth
- Address active mechanistic questions raised by translational research leads across solid and hematologic indications
- Direct laboratory research into program efficacy, failure, and resistance development
- Design and evaluate combination approaches to increase treatment benefit and counter resistance
- Establish and operate the laboratory while bringing disease-area scientists together under unified leadership
- Oversee omics, functional and perturbation biology, in vitro and in vivo studies, and organoid platforms
- Participate in the Core Senior Leadership Team for Translational Research and help shape organization-wide scientific strategy
- Act as the scientific connection between reverse translation and Discovery
- Partner with Medical Affairs and Commercial on lifecycle and portfolio priorities
- Lead mechanism-focused translational research publications, including the Mechanism Series
- Mentor scientists and foster rigorous, open scientific debate
- Evaluate team performance by its influence on program and portfolio decisions
आवश्यकताएँ
- Doctorate in cancer biology, molecular biology, immunology, pharmacology, or a related discipline, such as a PhD, MD, or MD/PhD
- At least 10 years of experience for Senior Director consideration or 12 years for Executive Director consideration in oncology discovery or translational research, including direct laboratory leadership
- Broad expertise in mechanisms and mechanisms of resistance, with demonstrated success converting clinical observations into testable laboratory hypotheses
- Experience building and managing wet-lab teams and operating omics and functional-characterization platforms
- Ability to work effectively at the Discovery–Translational Research interface within a matrix spanning multiple disease areas
- Strong publication history, including first- or last-author papers, combined with clear scientific communication
- Preferred: expertise in multiomics, perturbation biology, organoid models, and computational data integration
- Preferred: experience extracting portfolio-relevant insights from shelved programs
- Preferred: record of developing combination and resistance-reversal strategies across modalities
- Preferred: experience collaborating with Medical Affairs and Commercial on lifecycle-focused science
लाभ
- Pension retirement plan
- 401(k) savings plan
- Long-term incentive program
- 120 hours of vacation per calendar year
- 40 hours of sick time per calendar year, with 48 hours for Colorado employees and 56 hours for Washington employees
- 13 paid holidays, including floating holidays, per calendar year
- Up to 40 hours of work, personal, and family time per calendar year
- 480 hours of parental leave within one year of a child's birth, adoption, or placement in foster care
- Bereavement leave of 240 hours for an immediate family member or 40 hours for an extended family member per calendar year
- 80 hours of caregiver leave during a rolling 52-week period
- 32 hours of volunteer leave per calendar year
- 80 hours of military spouse time off per calendar year
- Inclusive interviews and support for workplace accommodations
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