GSK is a global healthcare and pharmaceutical company that combines scientific research, technology, and specialist talent to develop medicines and vaccines. Its work spans the discovery, production, and delivery of products designed to help prevent and manage disease, offering opportunities to contribute to healthcare innovation within a large, international organization.
Director of Portfolio Management, GSK – London Hybrid
Guide GSK’s pharmaceutical pipeline investment decisions across preclinical research and clinical development. Apply economic modelling, risk analysis, and advanced analytics to support senior governance and portfolio choices.
Description
- Support the Head of Portfolio Decision Sciences, RI&I, across the full R&D lifecycle from preclinical research through late-stage clinical development
- Assess investment opportunities amid substantial uncertainty and limited data through structured risk analysis and probability-based evaluation
- Prepare economic assessments, including ROI and NPV analyses, for development options and scenarios
- Partner with pipeline teams and governance boards to guide technical progression and investment decisions
- Deliver impartial assessments of individual projects for R&D investment planning
- Advise investment body chairs using option analysis, value-risk evaluation, and resource optimisation
- Lead portfolio- and indication-level reviews to inform prioritisation and investment choices
- Evaluate assets using external market intelligence, sell-side benchmarks, and competitor comparisons
- Contribute to RI&I’s twice-yearly dynamic Portfolio Review process
- Work across portfolio management, finance, Research Unit leadership, strategy, project management, and operations
- Propose near- and long-term priorities along with approaches to reduce risk
- Track developments in portfolio management and recommend new decision-making practices
- Advance and apply analytics capabilities, including artificial intelligence and machine learning, to portfolio decisions
Requirements
- Professional experience in pharmaceuticals, healthcare, or a related sector
- Bachelor’s degree in a relevant discipline
- Working knowledge of commercial and/or R&D processes
- Experience leading or supporting drug development project teams is preferred
- Demonstrated ability to deliver projects independently
- Strong matrix-management capability and effectiveness within senior cross-functional teams
- Capacity to manage several projects and competing priorities
- Strong coordination, planning, teamwork, and strategic-thinking abilities
- Clear communication and negotiation skills across audiences, including senior leaders
- Ability to influence others while maintaining personal resilience
- Enough drug-development expertise to engage R&D leaders as a peer, challenge plans constructively, and shape decisions without formal authority
- Structured and methodical approach to solving problems
- Ability to create and compare multiple options, strategies, and contingency plans
- High learning agility
- PhD, MBA, or another advanced degree is preferred
- Strong written and spoken communication
- Experience managing cross-functional stakeholders
- Evidence of successfully enabling and leading change
Benefits
- Hybrid arrangement combining office-based and remote work
- Agile work environment with opportunities for flexibility
- Equal-opportunity employment
- Recruitment-process adjustments and support are available