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Pfizer is a global pharmaceutical company focused on developing and providing medicines and healthcare services that support health throughout life. Its work spans scientific innovation and access to safe, effective, and affordable treatments, with a particular emphasis on advancing therapies for cancer and other significant health conditions. The company’s profile may be relevant to professionals exploring careers in pharmaceutical research, healthcare, and related commercial functions.
Head of AI Clinical Excellence at Pfizer
Lead Pfizer’s AI strategy across clinical development, applying analytics and automation to improve trial operations and decision-making. Guide AI governance, regulatory alignment, and cross-functional innovation in a hybrid role.
Description
- Set Pfizer’s enterprise strategy for AI-enabled clinical excellence across Clinical Development.
- Find ways AI can shorten development timelines, raise quality, reduce operational burden, and improve decisions.
- Advise senior leaders on emerging AI capabilities, industry trends, and competitive developments.
- Expand AI use across study design, protocol optimization, feasibility, patient recruitment, trial execution, and clinical data review.
- Lead AI initiatives to improve trial performance, operational excellence, and portfolio decisions.
- Enable predictive and prescriptive analytics for program- and study-level decisions.
- Work with digital, data science, and technology teams to design, build, validate, and deploy AI tools and platforms.
- Create frameworks for scalable AI solutions embedded in clinical development workflows.
- Develop agentic and generative AI, predictive analytics, and workflow automation solutions for clinical operations and development teams.
- Advise on global regulatory expectations for AI, machine learning, and advanced analytics in drug development.
- Partner with Regulatory Affairs and Quality to establish AI governance, validation, and risk management approaches.
- Track changing health authority guidance and industry standards for AI-enabled development.
- Build partnerships across Oncology Clinical Development, Clinical Operations, Biostatistics, Regulatory Affairs, Medical, Safety, and Digital.
- Lead multidisciplinary teams delivering AI innovation initiatives.
- Support adoption through education, change management, and capability building.
- Represent Pfizer at industry forums, consortia, health authority discussions, and scientific conferences.
- Build relationships with external partners, technology providers, and academic collaborators.
- Travel occasionally as required.
Requirements
- MD plus at least 4 years of relevant experience in pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations; or a PhD in Life Sciences, Clinical Research, Data Science, Biostatistics, Computer Science, Engineering, or a related field plus at least 5 years of relevant experience in those organizations; or an MS in one of those fields plus at least 7 years of relevant experience.
- Experience designing, developing, and implementing AI, machine learning, or advanced analytics solutions in clinical research.
- Experience supporting Clinical Development, Clinical Operations, Clinical Science, Clinical Data Review, or Regulatory Science.
- Experience leading cross-functional programs with clinical, regulatory, scientific, and technical stakeholders.
- Strong knowledge of GCP, clinical trial conduct, drug development, and regulatory requirements.
- Ability to turn complex scientific or operational challenges into scalable technology-enabled solutions.
- Excellent communication and executive influencing skills.
- Expertise in Clinical Development, Oncology, Regulatory Science, Data Science, or Clinical Informatics.
- Experience developing and deploying large language models, generative or agentic AI systems, or workflow automation platforms in regulated settings.
- Oncology experience.
- Familiarity with emerging regulatory frameworks for AI-enabled drug development.
- Experience engaging with global regulatory agencies such as FDA, EMA, MHRA, PMDA, or Health Canada.
- Experience leading enterprise AI transformation initiatives.
- Strong publication record and scientific credibility in clinical research and AI innovation.
- Experience building and leading high-performing teams.
- Broad leadership experience, including influencing and collaborating with peers, coaching and developing others, and guiding colleagues toward meaningful outcomes and business impact.
- Must be authorized to work in the United States for any employer.
- Permanent U.S. work authorization is required.
- U.S. work visa sponsorship is not available now or in the future.
Benefits
- Pfizer Global Performance Plan with a target bonus of 20% of base salary.
- Share-based long-term incentive program.
- 401(k) plan with Pfizer matching contributions.
- Additional Pfizer retirement savings contribution.
- Paid vacation, holidays, and personal days.
- Paid caregiver, parental, and medical leave.
- Medical, prescription drug, dental, and vision coverage.
- Relocation assistance may be available based on business needs and eligibility.
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